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科学不是做秀(回复维生素E与肺癌)  

2008-03-28 00:01:08|  分类: 波子谈健康 |  标签: |举报 |字号 订阅

  下载LOFTER 我的照片书  |
 
 科学不是做秀
 
   昨天的《维生素E补充剂可致癌吗?》引起广泛的关注。尤其引起大多数迷信维生素的人关注。其实这是一篇很普通的科学论文,而且是今年2月份就已经在西方世界发表了,为什么会引起这么大反应呢?我不想说的太多,我担心的是再次伤了善良人的感情。让大家去冷静思考!其实大家仔细阅读,再次阅读就会知道文章是说什么,怎么说。昨天南方日报的朋友也在问我这个问题,也许他会给大家答案。在这里我要回答的文章出处。
 
  关于VE与肺癌的报道分别在今年2月在英美均有报道,大家可以从这里去阅读这些文章:
   Vitamin Esupplements 'could cause up to 27 per cent increase in lungcancer'. Daily Mail, February 29 2008


   Vitamin E linked to lungcancer. BBC News, February 29 2008


    Nutritionand Lung Cancer: Lessons from the Differing Effects of Foods andSupplements.


Tim Byers. Am J Respir Crit Care Med. 2008; 177:470-471
 
   如果大家认为我的文章是拍脑袋写出来,或者是哗众取宠的,那么就读该文的原文:

    Theresearchers concluded that no supplement protected against lungcancer; however, vitamin E was associated with a small increase inrisk, most prominently in smokers.
 
    最后,我想对大家说一句话:遵循毛泽东先生的教导:“医生的话不能不听,也不能全听”,用您的智慧去判断每一件事,不要人云亦云,也不要盲目迷信,物极必反!
 
[参考附件]
Vitamin E Supplements May Raise Lung CancerRisk

Vitamin supplements won't protect people against lung cancer andtaking vitamin E may even heighten the risk, a new study finds.

The survey covered the supplement-taking habits and lung cancerincidence of almost 78,000 adults in the state of Washington over afour-year period.

"Our study of supplemental multivitamins, vitamin C, vitamin Eand folate did not show any evidence for a decreased risk of lungcancer," study author Dr. Christopher G. Slatore, a fellow in thedivision of pulmonary and critical care medicine at the Universityof Washington, said in a statement. "Indeed, increasing intake ofsupplemental vitamin E was associated with a slightly increasedrisk of lung cancer."

As reported in the March issue of the American Journal ofRespiratory and Critical Care Medicine, the research focused on menand women aged 50 to 76 taking part in the four-year VITAmins andLifestyle (VITAL) study. Lung cancer was diagnosed in 521participants surveyed.

In addition to the expected association with smoking, familyhistory and other lung cancer risk factors, there was a slight butstatistically significant association with vitamin Esupplementation and incidence of the disease, the researchersfound.

Every increase in vitamin E of 100 milligrams per day wasassociated with a 7 percent rise in lung cancer risk -- translatinginto a 28 percent increase in risk over 10 years for someone taking400 milligrams of vitamin E daily.

"This provides additional evidence that taking vitaminsupplements does not help prevent lung cancer," said Eric Jacobs,strategic director of pharmacoepidemiology at the American CancerSociety.

The society does not currently recommend use of any vitaminsupplement to prevent malignancy, Jacobs said. However, "ourdietary guidelines do recommend eating five or more servings of avariety of vegetables each day," he noted.

A representative of the supplements industry called the studyresults "not all that surprising."

"Vitamins are essential nutrients that act to maintain healthand prevent vitamin deficiency," Pamela Mason, spokeswoman for theLondon-based Health Supplements Information Service, said in astatement. "They were never intended to be used to prevent chronicdisease such as cancer. Indeed, it would be asking a lot of avitamin pill to expect it to prevent cancer."

Since the primary cause of lung cancer is smoking, the bestpreventive measure is simply not to smoke, Jacobs said. Nutrientscan play an auxiliary role, he noted. Anyone who cannot quit shouldavoid taking beta-carotene supplements, because studies have linkedthem to an increased risk of lung cancer, Jacobs said.

On the other hand, "for former smokers, there is some evidencethat vegetables high in carotinoids, such as carrots and sweetpeas, decrease the risk," he said.

Some vitamins have been linked to a reduced risk of othercancers, added Edward Gorham, an associate professor of family andpreventive medicine at the University of California at SanDiego.

"We have worked with vitamin D, and we found a protective effectof vitamin D on colon cancer, breast cancer and ovarian cancer, andrecently a modest effect on lung cancer," Gorham said.

But that effect came not from supplements but from sunlight,which causes vitamin D to be formed in the human body, he said.

"These results with multivitamins dont surprise me because thereis so little vitamin D in multi-supplements, 100 or 200International Units," Gorham said. "To achieve the effect, it takes2,000 IU. If youre in the tropics, that amounts to 10 or 15 minutesin the sun. In southern California, it takes 10 or 15 minutes inthe summer and longer in the winter because the sun angle is solow."

One study has also associated vitamin D supplements with adecreased risk of colon and breast cancer in women, Gorhamsaid.

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